Apireks surup

Last updated on For the relief of mild to moderate pain including rheumatic and muscular pain, backache, neuralgia, migraine, headache, dental pain, dysmenorrhoea, feverishness and for the apireks surup of the symptoms of cold and influenza. For the relief of migraine-headaches, apireks surup, backache, dental pain, neuralgia and period pains as well as rheumatic and muscular pains.

Apireks Suspension Generic Name s : Ibuprofen. Why it's used Apireks Suspension is used to relieve mild to moderate pain from a headache , menstrual periods, muscle ache, common cold , toothache, or a backache. This medicine works by reducing the activity of a chemical in the body that causes pain and swelling. Apireks is also used to reduce fever. It is also used to relieve pain associated with the inflammation, swelling and stiffness of the joints caused by rheumatoid arthritis and osteoarthritis. When not to use Apireks Suspension cannot be used to treat pain before and after the time of a heart operation.

Apireks surup

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As with other NSAIDs, long-term administration of ibuprofen has resulted in renal papillary necrosis and other renal pathologic changes, apireks surup. Brufen is contraindicated in patients with hypersensitivity to the active substance or to any of the excipients. Gastrointestinal Bleeding, Ulceration, And Perforation NSAIDs, including ibuprofen, cause serious gastrointestinal GI adverse events including inflammation, bleeding, ulceration, and perforation of the esophagus, stomach, small intestine, or apireks surup intestine, which can be fatal.

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Apireks is a non-selective inhibitor of cyclooxygenase, an enzyme invovled in prostaglandin synthesis via the arachidonic acid pathway. Its pharmacological effects are believed to be due to inhibition cylooxygenase-2 COX-2 which decreases the synthesis of prostaglandins involved in mediating inflammation, pain, fever and swelling. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation. Inhibition of COX-1 is thought to cause some of the side effects of ibuprofen including GI ulceration. Apireks is administered as a racemic mixture. The R-enantiomer undergoes extensive interconversion to the S-enantiomer in vivo. The S-enantiomer is believed to be the more pharmacologically active enantiomer.

Apireks surup

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The use of this medicine may change blood pressure. Although it is probably more likely to occur in patients with systemic lupus erythematosus and related connective tissue diseases, it has been reported in patients who do not have underlying chronic disease. The information provided in Undesirable effects of Apireks is based on data of another medicine with exactly the same composition as the Apireks. This is reversible on withdrawal of treatment. Nonsteroidal anti-inflammatory drugs, also called as NSAIDs , help reduce fever , decrease pain , and prevent clotting of blood. Consider withdrawal of NSAIDs, including Apireks in women who have difficulties conceiving or who are undergoing investigation of infertility. Erythema multiforme, bullous reactions, including Stevens-Johnson syndrome,and toxic epidermal necrolysis. If visibly opaque particles, discoloration or other foreign particulates are observed, the solution should not be used. This medicine increases the risk of stomach bleeding and rupture in the lining of the stomach or intestine in elderly patients. When taken with food, peak levels are observed after 1 to 2 hours. Dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Inform patients not to use low-dose aspirin concomitantly with Apireks until they talk to their healthcare provider. The management of ibuprofen overdose is primarily supportive.

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Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine. Read more: What are the uses of Apireks? Use while Breastfeeding Consult with your doctor on the use of Apireks Suspension during breastfeeding. Chlorhexidine must not be used to disinfect the neck of the ampoule as it is not compatible with the Apireks solution. In these patients, administration of an NSAID may cause a dose dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation. Do not take more than 6 caplets in any 24 hour period. Correct volume status in dehydrated or hypovolemic patients prior to initiating Apireks. Apireks may alter the usual signs of infection. Pregnant Women Precaution. You are much safer by always keeping a fresh supply of unexpired medicines.