apoprotein

Apoprotein

Apoproteins are the proteins of lipoproteins, apoprotein. The functions of several apoprotein known to regulate lipolytic enzyme activities and lipoprotein uptake into cells.

Apolipoproteins are proteins that bind lipids oil-soluble substances such as fats, cholesterol and fat soluble vitamins to form lipoproteins. They transport lipids in blood, cerebrospinal fluid and lymph. The lipid components of lipoproteins are insoluble in water. However, because of their detergent-like amphipathic properties, apolipoproteins and other amphipathic molecules such as phospholipids can surround the lipids, creating a lipoprotein particle that is itself water-soluble, and can thus be carried through body fluids i. In addition to stabilizing lipoprotein structure and solubilizing the lipid component, apolipoproteins interact with lipoprotein receptors and lipid transport proteins, thereby participating in lipoprotein uptake and clearance. They also serve as enzyme cofactors for specific enzymes involved in the metabolism of lipoproteins.

Apoprotein

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Apoprotein of Lipid Research. Basic amino acids important for LDL receptor binding are clustered into a surface patch on one long helix, apoprotein.

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Apoprotein, also known as apolipoprotein, is a protein that associates with lipids such as cholesterol and phospholipids to form lipoprotein complexes. Lipoproteins are essential for transporting lipids in the bloodstream, including cholesterol and triglycerides, which are insoluble in water and require transport vehicles for efficient circulation in the blood. Apoprotein, also known as apolipoprotein, is a protein component found in association with lipids, particularly in the context of lipoprotein complexes. These proteins are essential for the transportation of lipids, including cholesterol and triglycerides, in the bloodstream. Apoproteins play crucial roles in lipid metabolism, including facilitating the assembly, stabilization, and recognition of lipoproteins, as well as regulating enzyme activity involved in lipid processing. In essence, apoproteins are protein components of lipoproteins that enable the efficient transport and metabolism of lipids throughout the body.

Apoprotein

Federal government websites often end in. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. NCBI Bookshelf. Sridevi Devaraj ; Jennifer R. Semaan ; Ishwarlal Jialal. Authors Sridevi Devaraj 1 ; Jennifer R. Semaan 2 ; Ishwarlal Jialal 3. Lipids such as cholesterol are insoluble in plasma, and for delivery to tissues such as the adrenal gland, gonads, etc.

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American Journal of Physiology. Bibcode : Sci Neurobiology of Aging. Apolipoproteins are also exploited by hepatitis C virus HCV to enable virus entry, assembly, and transmission. June Apolipoprotein D apoD is a soluble carrier protein of lipophilic molecules in neurons and glial cells within the central and peripheral nervous system and apoD can also modulate the stability and oxidation status of these molecules. Ageing Research Reviews. Basic amino acids important for LDL receptor binding are clustered into a surface patch on one long helix. The functions of several are known to regulate lipolytic enzyme activities and lipoprotein uptake into cells. Proteins that bind lipids to transport them in body fluids. For example, apoA5 is also known as apo A-V. The lipid components of lipoproteins are insoluble in water. ApoD level increases in nervous system with a large number of neurologic disorders inclusive of Alzheimer's disease, schizophrenia, and stroke. Journal of Thrombosis and Haemostasis.

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The turnover of the apo-C group of apoproteins was not affected by overweight. Clinical Chemistry and Laboratory Medicine. May ApoC3 is a risk factor of cardiovascular disease. Frontiers in Immunology. Apolipoprotein B plays a particularly important role in lipoprotein transport being the primary organizing protein of many lipoproteins. For example, apoA5 is also known as apo A-V. Journal of Lipid Research. Thus, despite increased production of triglyceride with fatness, there was no concomitant increased formation of the main protein B of triglyceride-rich VLDL, nor in that of the major catabolic protein apo-CII that initiates triglyceride removal. Category : Apolipoproteins. Article Talk. Apoproteins are the proteins of lipoproteins. Read Edit View history.

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