Cellosaurus

This post was co-authored by Susanna Stroik and Rachel Leeson. Here at Addgene, cellosaurus, we like to help share useful new resources with the scientific community cellosaurus particularly ones that help address ongoing problems, cellosaurus, like cells lines. A cellosaurus in Science found that approximately one-third of cell lines used in scientific research are misidentified!

Despite an increased awareness of the problematic of cell line cross-contamination and misidentification, it remains nowadays a major source of erroneous experimental results in biomedical research. To prevent it, researchers are expected to frequently test the authenticity of the cell lines they are working on. STR profiling was selected as the international reference method to perform cell line authentication. While the experimental protocols and manipulations for generating a STR profile are well described, the available tools and workflows to analyze such data are lacking. The Cellosaurus knowledge resource aimed to improve the situation by compiling all the publicly available STR profiles from the literature and other databases. As a result, it grew to become the largest database in terms of human STR profiles, with 6, distinct cell lines having an associated STR profile release July 31,

Cellosaurus

We have developed an online database describing the known cell lines from Coleoptera, Diptera, Hemiptera, Hymenoptera, and Lepidoptera that were developed from agricultural pests. Cell line information has been primarily obtained from previous compilations of insect cell lines. Here, we report on a new database of insect cell lines, which covers cell lines from 86 species. We provide the designation, tissue and species of origin, cell line developer, unique characteristics, its use in various applications, publications, and patents, and, when known, insect virus susceptibility. Despite an increased awareness of the problematic of cell line cross-contamination and misidentification, it remains nowadays a major source of erroneous experimental results in biomedical research. To prevent it, researchers are expected to frequently test the authenticity of the cell lines they are working on. STR profiling was selected as the international reference method to perform cell line authentication. While the experimental protocols and manipulations for generating a STR profile are well described, the available tools and workflows to analyze such data are lacking. The Cellosaurus knowledge resource aimed to improve the situation by compiling all the publicly available STR profiles from the literature and other databases. As a result, it grew to become the largest database in terms of human STR profiles, with 6, distinct cell lines having an associated STR profile release July 31,

Here at Addgene, we like to help share useful new resources with the scientific community — particularly ones that help address ongoing problems, cellosaurus cells lines, cellosaurus.

Cellosaurus is an online knowledge base on cell lines , which attempts to document all cell lines used in biomedical research. Its scope includes immortalised cell lines , naturally immortal cell lines example: embryonic stem cells and finite life cell lines when those are distributed and used widely. The Cellosaurus provides a wealth of manually curated information; for each cell line it lists a recommended name, synonyms and the species of origin. Other types of information include standardised disease terminology for cancer or genetic disorder cell lines , the transformant used to immortalise a cell line, transfected or knocked-out genes, microsatellite instability , doubling time , gender and age of donor patient or animal , important sequence variations, web links, publication references and cross-references to close to different databases, ontologies, cell collections and other relevant resources. Since many cell lines used in research have been misidentified or contaminated , the Cellosaurus keeps track of problematic cell lines, including all those listed in the International Cell Line Authentication Committee ICLAC [8] tables. For human as well as some dog cell lines, it provides short tandem repeat STR profile information.

Federal government websites often end in. The site is secure. The Cellosaurus is a knowledge resource on cell lines. It aims to describe all cell lines used in biomedical research. Its scope encompasses both vertebrates and invertebrates.

Cellosaurus

Cellosaurus is an online knowledge base on cell lines , which attempts to document all cell lines used in biomedical research. Its scope includes immortalised cell lines , naturally immortal cell lines example: embryonic stem cells and finite life cell lines when those are distributed and used widely. The Cellosaurus provides a wealth of manually curated information; for each cell line it lists a recommended name, synonyms and the species of origin. Other types of information include standardised disease terminology for cancer or genetic disorder cell lines , the transformant used to immortalise a cell line, transfected or knocked-out genes, microsatellite instability , doubling time , gender and age of donor patient or animal , important sequence variations, web links, publication references and cross-references to close to different databases, ontologies, cell collections and other relevant resources. Since many cell lines used in research have been misidentified or contaminated , the Cellosaurus keeps track of problematic cell lines, including all those listed in the International Cell Line Authentication Committee ICLAC [8] tables. For human as well as some dog cell lines, it provides short tandem repeat STR profile information. Since July , cell lines in the Cellosaurus are represented as items in Wikidata. The Cellosaurus encyclopedia is widely recognized as an authoritative source for cell line information, providing unique identifiers [10] [11] and as source of curated information. Contents move to sidebar hide. Article Talk.

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Bairoch, A. Contributing to Cellosaurus Generated a new cell? Journal of Biomolecular Techniques. As a result, it grew to become the largest database in terms of human STR profiles, with 6, distinct cell lines having an associated STR profile release July 31, To prevent it, researchers are expected to frequently test the authenticity of the cell lines they are working on. Retrieved The Cellosaurus knowledge resource aimed to improve the situation by compiling all the publicly available STR profiles from the literature and other databases. You can look up the cell lines you are currently or planning to use for helpful information on the known features and relevant literature, or to decide which line is best for your experiments. Sharing science just got easier Substances Biomarkers. Abstract Despite an increased awareness of the problematic of cell line cross-contamination and misidentification, it remains nowadays a major source of erroneous experimental results in biomedical research. It may require cleanup to comply with Wikipedia's content policies, particularly neutral point of view. Swiss Institute of Bioinformatics. We provide the designation, tissue and species of origin, cell line developer, unique characteristics, its use in various applications, publications, and patents, and, when known, insect virus susceptibility. It aims to help researchers in the process of cell line authentication by providing numerous functionalities.

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Other types of information include standardised disease terminology for cancer or genetic disorder cell lines , the transformant used to immortalise a cell line, transfected or knocked-out genes, microsatellite instability , doubling time , gender and age of donor patient or animal , important sequence variations, web links, publication references and cross-references to close to different databases, ontologies, cell collections and other relevant resources. Despite an increased awareness of the problematic of cell line cross-contamination and misidentification, it remains nowadays a major source of erroneous experimental results in biomedical research. PMID J Biomol Tech. Database Profile Cellosaurus. Add Comment. Tags Other. If the information seems incomplete or unclear, Bairoch follow up via email to the authors of the paper in which the cell line was described. July Learn how and when to remove this template message. The Cellosaurus provides a wealth of manually curated information; for each cell line it lists a recommended name, synonyms and the species of origin.