Cupriavidus metallidurans

Type strain:. Culture col. Strain history: CIP. Cupriavidus metallidurans CH34 is a facultative anaerobe, mesophilic, Gram-negative bacterium that was isolated from decantation tank of zink factory, cupriavidus metallidurans.

Federal government websites often end in. The site is secure. We describe the first case of invasive human infection a nosocomial septicemia caused by Cupriavidus metallidurans. This metal-resistant bacterium has not been reported to be pathogenic in humans or animals. A year-old Caucasian man, known to have type 2 diabetes, arteriosclerotic heart disease, dyslipidemia, arterial hypertension, and obesity kg , underwent a radical cystoprostatectomy with ileal duct and ileostomy for a vesical high-grade carcinoma with four pelvic lymph nodes positive for neoplasia. A subtotal pancreatectomy and splenectomy were performed simultaneously for a pancreatic neuroendocrine tumor. In each instance, the patient was treated with antimicrobial agents and drainage.

Cupriavidus metallidurans

Federal government websites often end in. The site is secure. Recent discovery on the potential use of a bacterium has revealed that it can yield carat gold in one week. Scientists from Michigan State University, USA, Kazem Kashefi, assistant professor of microbiology and Adam Brown, associate professor of electronic art and intermedia, found that a bacterium, Cupriavidus metallidurans previously known as Ralstonia metallidurans [ 1 ] that belongs to beta class of proteobacteria can grow on a substantial concentration of toxic gold chloride also known as liquid gold. The bacterium with such potential was first isolated in from the sludge of a metal processing factory located in Belgium [ 3 ]. Its ability to detoxify gold complexes by transforming them into metallic gold was discovered in [ 4 ]. When discovered, the bacterium was initially found to be resistant to cadmium but subsequent studies identified that this strain is multi-metal resistant and has two plasmids pMOL28 and pMOL30 which harbor multiple loci for metal resistance [ 5 ]. Such unique ability of this extremophile to metabolize toxic substances might also provide an insight into understanding the origin of life. This microbial magician, C. The art work consists of a portable lab which consists of a glass bioreactor containing the bacteria.

D-tartrate as carbon source DTAT, cupriavidus metallidurans. Clinical and Laboratory Standards Institute The nucleotide sequence of the mercuric resistance operons of plasmid R and transposon Tn further evidence for mer genes which enhance the activity of the mercuric ion detoxification system.

Cadmium is a highly toxic heavy metal for biological systems. Cupriavidus metallidurans CH34 is a model strain to study heavy metal resistance and bioremediation as it is able to deal with high heavy metal concentrations. The aim of this study was to characterize the response of C. Inhibition of the initiation of biofilm formation and EPS production by C. Planktonic and biofilm cells showed similar tolerance to cadmium. During exposure to cadmium an acute decrease of c-di-GMP levels in planktonic and biofilm cells was observed.

Federal government websites often end in. The site is secure. Cupriavidus metallidurans has been mostly studied because of its resistance to numerous heavy metals and is increasingly being recovered from other environments not typified by metal contamination. They host a large and diverse mobile gene pool, next to their native megaplasmids. Here, we used comparative genomics and global metabolic comparison to assess the impact of the mobilome on growth capabilities, nutrient utilization, and sensitivity to chemicals of type strain CH34 and three isolates NA1, NA4 and H The mobilome was expanded as prophages were predicted in NA4 and H, and a genomic island putatively involved in abietane diterpenoids metabolism was identified in H No correlation between the mobilome and isolation environment was found. In addition, our comparison indicated that the metal resistance determinants and properties are conserved among these strains and thus maintained in these environments. Furthermore, all strains were highly resistant to a wide variety of chemicals, much broader than metals.

Cupriavidus metallidurans

Copper Cu is important for plant growth, but high concentrations can lead to detrimental effects such as primary root length inhibition, vegetative tissue chlorosis, and even plant death. The interaction between plant-soil microbiota and roots can potentially affect metal mobility and availability, and, therefore, overall plant metal concentration. Cupriavidus metallidurans CH34 is a multi metal-resistant bacterial model that alters metal mobility and bioavailability through ion pumping, metal complexation, and reduction processes. The interactions between strain CH34 and plants may affect the growth, metal uptake, and translocation of Arabidopsis thaliana plants that are exposed to or not exposed to Cu.

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Species of bacterium. We describe the first case of invasive human infection a nosocomial septicemia caused by Cupriavidus metallidurans. Strain identifier. Lovering, A. Park, S. In planktonic cells, the expression of two genes changed significantly in response to cadmium. The genomic context of CH34 c-di-GMP pathway genes and genes related to heavy metal resistance, motility, and biofilm formation was analyzed. Katoh, K. Biomineralization of gold: biofilms on bacterioform gold. After 45 min incubation in presence or absence of cadmium, 9 of the 10 mL of planktonic culture were collected, leaving 1 mL for total protein content determination. In this study, plasmids pJB3Tc19 Blatny et al. D-trehalose as carbon source TRE.

Federal government websites often end in. The site is secure. Recent discovery on the potential use of a bacterium has revealed that it can yield carat gold in one week.

Only first 5 entries are displayed. Cyclic diguanylate is a ubiquitous signaling molecule in bacteria: insights into biochemistry of the GGDEF protein domain. The site is secure. Christensen J. Cadmium is a highly toxic heavy metal for biological systems. No environmental cultures were performed, and the means of transmission is unknown. As a library, NLM provides access to scientific literature. Geer, L. Characterization of the metabolically heavy metal-resistant Cupriavidus metallidurans strain MSR33 generated for mercury remediation. The drop of c-di-GMP levels inhibits the cell adhesion pilus and extracellular polysaccharide synthesis cellulose and Pel that may favor the planktonic lifestyle. HAMP domain rotation and tilting movements associated with signal transduction in the PhoQ sensor kinase. Lin, T. Top bar navigation.