Durater 40 mg
Aspiration prophylaxis in patients undergoing anesthesia off-label use : Note: May be considered in patients at high risk for aspiration Ref :, durater 40 mg. Erosive esophagitis due to gastroesophageal reflux disease alternative agent : Note: Although a labeled indication, H 2 -receptor antagonists eg, famotidine are not preferred for the durater 40 mg of erosive esophagitis due to gastroesophageal reflux disease due to the availability of proton pump inhibitors PPIs Ref. Oral: 20 or 40 mg twice daily for up to 12 weeks.
Official websites use. Share sensitive information only on official, secure websites. Prescription famotidine is used to treat ulcers sores on the lining of the stomach or small intestine ; gastroesophageal reflux disease GERD, a condition in which backward flow of acid from the stomach causes heartburn and injury of the esophagus [tube that connects the mouth and stomach] ; and conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome tumors in the pancreas or small intestine that cause increased production of stomach acid. Over-the-counter famotidine is used to prevent and treat heartburn due to acid indigestion and sour stomach caused by eating or drinking certain foods or drinks. Famotidine is in a class of medications called H 2 blockers. It works by decreasing the amount of acid made in the stomach. Prescription famotidine comes as a tablet and a suspension liquid to take by mouth.
Durater 40 mg
How to take care of children With chickenpox With earache With gastroenteritis Umbilical cord care More options This page contains a list of brands of authorized pharmaceutical specialties of the active principle famotidine in the countries listed below:. Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. Famotidine is a drug belonging to the group of drugs called antagonists H2 or H2 receptor blockers. These drugs are used to treat diseases which are associated with the acid the stomach. Your doctor has prescribed famotidine to treat an ulcer , a gastroesophageal reflux disease GERD or a rare disease called Zollinger-Ellison syndrome. Famotidine is also used to decrease the chance of reappearing an ulcer or symptoms of gastroesophageal reflux disease. Medizzine recommends consulting your doctor if you are unsure or you do not know why you have been given famotidine. Some brands also include lactose as an excipient. Effervescent granules : In addition to famotidine, other ingredients excipients are anhydrous citric acid, sodium bicarbonate, sodium carbonate anhydrous sodium, sodium citrate, sorbitol E and aspartame E The composition of the various presentations may vary from one country to another.
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Famotidine , sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. Common side effects include headache, intestinal upset, and dizziness. Famotidine was patented in and came into medical use in Famotidine has a delayed onset of action, beginning after 90 minutes. However, famotidine has a duration of effect of at least minutes 9. At its peak effect, minutes 3. The most common side effects associated with famotidine use include headache , dizziness , and constipation or diarrhea.
Last updated on Durater injection, supplied as a concentrated solution for intravenous injection, is intended for intravenous use only. Durater injection is indicated in some hospitalized patients with pathological hypersecretory conditions or intractable ulcers, or as an alternative to the oral dosage forms for short term use in patients who are unable to take oral medication for the following conditions:. In some hospitalized patients with pathological hypersecretory conditions or intractable ulcers, or in patients who are unable to take oral medication, Durater injection may be administered until oral therapy can be instituted. The doses and regimen for parenteral administration in patients with GERD have not been established. While published uncontrolled clinical studies suggest effectiveness of Durater in the treatment of peptic ulcer, data in pediatric patients are insufficient to establish percent response with dose and duration of therapy.
Durater 40 mg
Durater is a histamine H2-receptor antagonist. Durater completely inhibits the action of histamine on H2-receptors of parietal cell. It inhibits basal, overnight and pentagastrin stimulated gastric acid secretion. The H2-receptor antagonist activity of Durater is slowly reversible, since the drug dissociates slowly from H2-receptor. Durater decreases the production of gastric acid, suppresses acid concentration and pepsin content, and decreases the volume of gastric secretion. Durater inhibits both basal and nocturnal gastric acid secretion, as well as acid secretion stimulated by food, caffeine, insulin, and pentagastrin. Durater has a dose-dependent therapeutic action, with the highest dose having the most extended duration of action and the highest inhibitory effect on gastric acid secretion. Following oral administration, the onset of action is within one hour, and the peak effect is reached within hours. The duration of effect is about hours. Histamine acts as a local hormone that stimulates the acid output by parietal cells via a paracrine mechanism.
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Other Effects Systemic effects of Durater in the CNS, cardiovascular, respiratory or endocrine systems were not noted in clinical pharmacology studies. Famotidine is a competitive H2 receptor antagonist that inhibits basal, overnight, and pentagastrin-stimulated gastric acid secretion. In elderly patients, there are no clinically significant age-related changes in the pharma-cokinetics of Durater. The information provided in Contraindications of Durater is based on data of another medicine with exactly the same composition as the Durater. Acute Therapy : The recommended adult oral dosage for active benign gastric ulcer is 40 mg once a day at bedtime. This promotes local delivery of these drugs to receptors in the parietal cell membrane and increases bioavailibility. Like all medicines, famotidine can cause side effects, although not everybody gets them. Famotidine is currently the drug of choice for initial treatment and maintenance therapy in most patients with uncomplicated gastric or duodenal ulcer. Pharmacokinetics and dynamics of famotidine in patients with renal failure. When treatment with a histamine H 2 antagonist is needed, famotidine is one of the preferred agents due to its lower concentrations in breast milk Richter Peptic ulcer disease: Management. A ] Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name.
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Schaumburg, IL: Athenex; July Prescription famotidine comes as a tablet and a suspension liquid to take by mouth. June Symptomatic improvement and healing of endoscopically verified erosion and ulceration were studied in two additional trials. Pepcid Ac Systemic effects of Durater in the CNS, cardiovascular, respiratory or endocrine systems were not noted in clinical pharmacology studies. OTC labeling: When used for self-medication OTC , do not use if trouble or pain when swallowing food, vomiting with blood, or bloody or black stools; allergic to other acid reducers; kidney impairment; coadministration with other acid reducers. Consult your doctor or pharmacist before taking any medicine. A large epidemiological study has suggested an increased risk for developing pneumonia in patients receiving H 2 receptor antagonists; however, a causal relationship with famotidine has not been demonstrated. Famotidine [usan] H 2 -histamine antagonist famotidine induced adverse CNS reactions with long-standing secondary mania and epileptic seizures.
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