Ondansetron moa

Ondansetronondansetron moa, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy ondansetron moa, radiation therapyor surgery. Common side effects include diarrheaconstipationheadachesleepinessand itchiness. Ondansetron was patented in and approved for medical use in

Federal government websites often end in. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. NCBI Bookshelf. Alexandria Griddine ; Jeffrey S. Authors Alexandria Griddine 1 ; Jeffrey S. Bush 2.

Ondansetron moa

Official websites use. Share sensitive information only on official, secure websites. Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Ondansetron is in a class of medications called serotonin 5-HT 3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. Ondansetron comes as a tablet, a rapidly disintegrating dissolving tablet, film, and an oral solution liquid to take by mouth. The first dose of ondansetron is usually taken 30 minutes before the start of chemotherapy, 1 to 2 hours before the start of radiation therapy, or 1 hour before surgery. Additional doses are sometimes taken one to three times a day during chemotherapy or radiation therapy and for 1 to 2 days after the end of treatment. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ondansetron exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. If you are taking the rapidly disintegrating tablet, remove the tablet from the package just before you take your dose.

It is typically used after other antinausea drugs have failed.

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Federal government websites often end in. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. NCBI Bookshelf. Alexandria Griddine ; Jeffrey S. Authors Alexandria Griddine 1 ; Jeffrey S. Bush 2. Ondansetron is one of the medications most commonly used for the empiric treatment of nausea and vomiting. Ondansetron has excellent utility as an antiemetic drug, and it is effective against nausea and vomiting of various etiologies. Common uses of ondansetron include the prevention of chemotherapy-induced and radiation-induced nausea and vomiting, the prevention of postoperative nausea and vomiting, and off-label use for the prevention of nausea and vomiting associated with pregnancy.

Ondansetron moa

Excipient information presented when available limited, particularly for generics ; consult specific product labeling. Ondansetron is a selective 5-HT 3 -receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. Surgical patients: Infants and Children: 1 to 4 months: 0. Adult normal : 19 to 40 years: 0.

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Anesth Analg. The lower bioavailability is attributed to first-pass metabolism. AU : B1 [3]. Comment on this article. Medical toxicologist consultation may become necessary in the overdose. Breastfeeding Considerations: In a pharmacokinetic study, the relative infant exposure to ondansetron is less. Markham A, Sorkin EM. Dronabinol Nabilone Tetrahydrocannabinol cannabis. Due to the potential for dose-dependent QTc interval elongation, the FDA recommends EKG monitoring along with potassium and magnesium in susceptible populations, such as the elderly or other at-risk groups. However, you should not flush this medication down the toilet. Retrieved 11 February Choose 3. Neurogastroenterology and Motility. Christofaki M, Papaioannou A. Ondansetron is one of the medications most commonly used for the empiric treatment of nausea and vomiting.

Nausea and vomiting are common complaints seen by emergency department physicians and primary care clinicians daily. Other antiemetics that appear on this list with ondansetron include dexamethasone and metoclopramide.

Three open non-comparative studies have been conducted to assess the safety and efficacy of ondansetron in children receiving a variety of chemotherapy regimens. PMID Ondansetron may cause other side effects. Pediatric dosing is weight-based at 0. Drugs for the treatment of nausea and vomiting in adults in the emergency department setting. Ondansetron comes as a tablet, a rapidly disintegrating dissolving tablet, film, and an oral solution liquid to take by mouth. Antagonists: Adatanserin Agomelatine Atypical antipsychotics e. Ondansetron is one of several antiemetic drugs used during the vomiting phase of cyclic vomiting syndrome. TGA eBS. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.