Paul insel

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Paul insel

Paul Anthony Insel born is an American physician and pharmacologist. He has been the chief editor of four academic journals and is an elected fellow of the American Association for the Advancement of Science , American Society for Pharmacology and Experimental Therapeutics , and American Physiological Society. His research is primarily focused on G proteins. He attended George Washington University for two years [4] before attending the University of Michigan , where he graduated with his Doctor of Medicine in His next position was at the University of California, San Francisco as a research fellow and associate professor in pharmacology. Insel primarily researches G proteins , including G protein-coupled receptors , heterotrimeric G-proteins and G protein-regulated effectors. Cho as the editor of the Annual Review of Pharmacology and Toxicology in He remains the editor as of Insel was elected as a fellow of the British Pharmacological Society in His first marriage was to Lola Steinbaum in The couple had two daughters and divorced by Contents move to sidebar hide.

Annual Review of Pharmacology and Toxicology.

The system can't perform the operation now. Try again later. Citations per year. Duplicate citations. The following articles are merged in Scholar. Their combined citations are counted only for the first article.

Current work emphasizes GPCR expression by individual cell types and the contribution of particular GPCRs to cellular responses, in particular, in cells especially cancer cells and cancer-associated fibroblasts in the tumor microenvironment. We focus on previously unrecognized GPCRs as regulators of cell function and as novel therapeutic targets. Our current emphasis is on pancreatic cancer. Other efforts include the identification of therapeutic approaches for patients with COVID based on its pathobiology in the hosts. Front Pharmacol.

Paul insel

Account Options Ieiet. Paul M. Insel , Dr. Written for major and advanced non-major course offerings, Nutrition, Seventh Edition provides students with a comprehensive, current, and science-based introduction to nutrition concepts, guidelines, and functions. It's student-focused approach provides information about topics and issues that concern them -- a balanced diet, nutritional supplements, weight management, exercise, and much more. Throughout each chapter readers will engage with the latest dietary guidelines, scientific evidence, and national standards to help individuals follow a healthy dietary pattern at every life stage.

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Inflammation and thrombosis in COVID pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets. Clinical Pharmacology and Therapeutics. Molecular pharmacology Biochemistry Cell biology Signal Transduction. Sriram K, Insel PA. Nerve growth factor-stimulated neuronal differentiation induces changes in P2 receptor expression and nucleotide-stimulated catecholamine release. Articles 1—20 Show more. Adrenergic receptors in man: direct identification, physiologic regulation, and clinical alterations. Adrenoceptors: a convergence of thinking. Genetic variation at the human alpha2B-adrenergic receptor locus: role in blood pressure variation and yohimbine response. Hypertonic stress regulates T-cell function by the opposing actions of extracellular adenosine triphosphate and adenosine Shock. Caveolar microdomains of the sarcolemma: compartmentation of signaling molecules comes of age. Expression of fibrinogen receptors during activation and subsequent desensitization of human platelets by epinephrine.

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New insights regarding the regulation of chemotaxis by nucleotides, adenosine, and their receptors. Disruption of protein kinase A localization using a trans-activator of transcription TAT -conjugated A-kinase-anchoring peptide reduces cardiac function. Hypertonic stress regulates T-cell function by the opposing actions of extracellular adenosine triphosphate and adenosine. Science Signaling. Circulation Research. Receptor metabolism after irreversible blockade of receptors and in cells traversing the cell division cycle. The system can't perform the operation now. Bcl-2 protects lymphoma cells from apoptosis but not growth arrest promoted by cAMP and dexamethasone. G-Protein-coupled receptor-signaling components in membrane raft and caveolae microdomains Handbook of Experimental Pharmacology. Characterization of alpha 2-adrenergic receptors on human platelets using [3H]yohimbine. Int J Cancer. The beta-adrenergic receptor as a paradigm.