Pill with 500 on it

Methocarbamol tablet, USP, a carbamate derivative of guaifenesin, is a central nervous system CNS depressant with sedative and musculoskeletal relaxant properties. Its molecular weight is

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Pill with 500 on it

If you are a consumer or patient please visit this version. Methocarbamol Tablets, USP, a carbamate derivative of guaifenesin, is a central nervous system CNS depressant with sedative and musculoskeletal relaxant properties. The chemical name of methocarbamol is 3- 2-methoxyphenoxy -1,2-propanediol 1-carbamate and has the empirical formula C 11 H 15 NO 5. Its molecular weight is The structural formula is shown below. Methocarbamol is a white powder, sparingly soluble in water and chloroform, soluble in alcohol only with heating and propylene glycol, and insoluble in benzene and n -hexane. Each tablet for oral administration contains mg or mg methocarbamol. Inactive ingredients include colloidal silicon dioxide, croscarmellose sodium, lecithin, magnesium stearate, microcrystalline cellulose, povidone, polyvinyl alcohol, polyethylene glycol, sodium lauryl sulfate, talc and titanium dioxide. The mechanism of action of methocarbamol in humans has not been established, but may be due to general CNS depression. It has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber. In healthy volunteers, the plasma clearance of methocarbamol ranges between 0. Methocarbamol is metabolized via dealkylation and hydroxylation. Conjugation of methocarbamol also is likely. Essentially all methocarbamol metabolites are eliminated in the urine. Small amounts of unchanged methocarbamol also are excreted in the urine.

Small amounts of unchanged methocarbamol also are excreted in the urine.

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Pill with 500 on it

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Methocarbamol tablets, USP are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. Version Files Dec 22, 8 current download Jan 2, 7 download Dec 31, 6 download Oct 5, 5 download Dec 26, 4 download Jul 29, 3 download Jun 25, 2 download Jun 18, 1 download. Methocarbamol may inhibit the effect of pyridostigmine bromide. In post-marketing experience, deaths have been reported with an overdose of methocarbamol alone or in the presence of other CNS depressants, alcohol or psychotropic drugs. Safety and effectiveness of methocarbamol in pediatric patients below the age of 16 have not been established. Pharmacokinetics In healthy volunteers, the plasma clearance of methocarbamol ranges between 0. Methocarbamol does not directly relax tense skeletal muscles in man. Safe use of Methocarbamol has not been established with regard to possible adverse effects upon fetal development. In healthy volunteers, the plasma clearance of methocarbamol ranges between 0. In post-marketing experience, deaths have been reported with an overdose of methocarbamol alone or in the presence of other CNS depressants, alcohol or psychotropic drugs.

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Its molecular weight is It is also not known whether methocarbamol can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Methocarbamol may inhibit the effect of pyridostigmine bromide. Because methocarbamol may possess a general CNS-depressant effect, patients should be cautioned about combined effects with alcohol and other CNS depressants. Pregnancy Category C Animal reproduction studies have not been conducted with methocarbamol. Product Information. The mechanism of action of methocarbamol in humans has not been established, but may be due to general central nervous system CNS depression. Since methocarbamol may possess a general CNS depressant effect, patients receiving methocarbamol should be cautioned about combined effects with alcohol and other CNS depressants. Patients should be cautioned that methocarbamol may cause drowsiness or dizziness, which may impair their ability to operate motor vehicles or machinery. Methocarbamol mg — Adults: Initial dosage: 3 tablets 4 times a day Maintenance dosage: 2 tablets 4 times a day.