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The metabolic benefits associated with long-term physical activity are well appreciated and growing evidence suggests that it involves the gut microbiota. Here we re-evaluated the link between exercise-induced microbial changes and those associated with prediabetes and diabetes. We found that the relative abundances of substantial amounts of diabetes-associated metagenomic species associated negatively with physical fitness in a Chinese athlete students cohort. We additionally showed that those microbial changes correlated more with handgrip strength, a simple but valuable biomarker suggestive of the diabetes states, than maximum oxygen intake, one of the key surrogates for endurance training. Moreover, the causal relationships among exercise, risks for diabetes, and gut microbiota were explored based on mediation analysis. We propose that the protective roles of exercise against type 2 diabetes are mediated, at least partly, by the gut microbiota. This is a preview of subscription content, log in via an institution to check access.
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India no match for China on r/chinalife indicators. Figure 5, r/chinalife. Gut microbiota modification: another piece in the puzzle of the benefits of physical exercise in health?
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The Outlook is Stable. The rating affirmation reflects NCI's adequate solvency buffer, strong growth in new business value and 'Most Favourable' company profile. Adequate Solvency Buffer: We expect NCI to retain an adequate surplus to support premium expansion and solvency stability. NCI has sustained an adequate capital buffer to underpin its new business expansion and investment volatility. NCI's risk-based capitalisation, as measured by Fitch's Prism Model, stayed in the 'Strong' category at end despite lower equity capital due to capital market volatility. However, with the adoption of the IFRS 17 and IFRS 9 new accounting standards in , we estimate the Prism score to have increased to a level well into the 'Strong' category in 1H23 when the contractual service margin is included as part of equity capital. Nonetheless, capital volatility continued to constrain NCI's ability to improve its operating profitability. NCI's unaudited net profit rose by 8.
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Footnotes Financial Disclosure: None to report. Wichmann, A. In , life expectancy was nine years longer in China than in India 74 versus 65 years Figure 1. State differences in infant mortality were similar, with Madhya Pradesh having the highest infant mortality rate of 61 deaths per 1, live births and Kerala the lowest rate of 13 data not shown [ 25 ]. Women in India had 2. Annual trends in life expectancy, infant, child, and maternal mortality rates were analyzed using the WHO, UN, and the World Bank databases that include current and time-trend data on health and human development variables for all nations, including China and India[ 1 , 9 - 11 ]. Unfavorable socioeconomic conditions and low human development levels can be a hindrance for public health improvement, but both India and China need to invest more in their health care infrastructure, provision of health services, and in education and rural sectors. With expanding industrialization and urbanization levels, people in both India and China are increasingly more likely to adopt lifestyles, dietary, and consumption patterns that are currently prevalent in the West[ 12 ]. Ouwerkerk, J. J Sport Health Sci 9 , 82— Shanghai and Beijing had the highest HDI scores of 0. Heyward, V. Hoffman, N.
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Koh, A. Figure 5. Yao, T. Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study. References Argyridou, S. Med Sci Sports Exerc 40 , — Provided by the Springer Nature SharedIt content-sharing initiative. Note: Cause-specific mortality rates are per , population and are age-adjusted to the world standard population. We used bivariate and multivariate ordinary least squares OLS regression models to estimate the impact of HDI, GII, and other socioeconomic factors on age-adjusted cervical cancer incidence and mortality rates. Reprints and permissions. Zhang, H. Accepted : 10 January Download citation.
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