Why was ru58841 abandoned

I started talking to some guys who said RU had some serious heart issues. Have any of your experienced this? I do not receive any compensation from any clinic. My comments are not medical advice.

Remember Me? Last Jump to page: Results 1 to 10 of Thread: RU Warning. Interstitial pneumonititis is a more common side effect of using DHT-blockers in the class of RU and nilutamide. This is a serious lung condition, which can be triggered by certain medications among other things. If left untreated, it can lead to permanent scarring of the lungs, such that you can no longer breath and can possibly die.

Why was ru58841 abandoned

Topical anti-androgens seem to gain popularity within the last year or so. Topical dutasteride and finasteride have become staples in many hair loss sufferers' protocols. Many world-renowned hair transplant surgeons believe topical anti-androgens will become the gold standard in the future, which leaves many questioning where RU falls in efficacy and safety. In this article, we will be talking about RU as a treatment for hair loss and how it compares to other topical anti-androgens. RU RU is a nonsteroidal antiandrogen developed in the s by a French pharmaceutical company. Initially, the drug was named ProStrakan while it was under investigation for androgen-related conditions such as acne, genetic hair loss, and excessive hair growth. This makes the medication appealing to those who have suffered from side effects for inhibiting their DHT systemically. A study published in the Journal of Dermatology compared the efficacy between topical RU and oral finasteride. The researchers did not use human subjects but rather used bald monkeys, which should be noted because the results may vary with humans. The researchers placed the monkeys in different groups the placebo, finasteride, and RU groups. The researchers tested the levels of serum DHT within the monkey's body. They noted a decrease in systemic DHT and an increase in testosterone from the finasteride group.

Also, what is up with all these cucky bro type dudes promoting it on Youtube? Sign up for a new account in our community.

We send out discount codes periodically to our subscribers. Jan 8, Hair loss can be a concern for many, and in the quest for solutions, RU has piqued the interest of those looking for effective remedies. With the buzz around this compound on the rise, there's a clear need for accurate information. In this post, we will try to provide straightforward answers to the common questions people have about RU , being a reliable resource for those seeking clarity on its uses and effects. RU is a substance that scientists developed in the early s, originally aiming to treat prostate cancer by applying it on the skin.

RegenRX, a company based in Tucson, AZ, has revealed that men and women may be able to get back the hair of their youth by using RU, which has been clinically proven to move the hair from the telogen phase or dormant phase to the anagen phase or growth phase. This may allow dormant hair follicles to become active again. RegenRX is offering RU for sale and clients have reported success after only three months of using RU once a day, with most clients noting the presence of signs of visible re-growth of hair after just two months. They have also reported that maximum growth thickness was attained at around six months of daily use. There are many possible causes of telogen effluvium, ranging from major stress to things like medications, childbirth, thyroid problems, surgery, and even weight loss. Fortunately, the condition is often temporary.

Why was ru58841 abandoned

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There was no evidence from those trials that RU was a superior drug, it was only a comparable drug. The only thing we do have is that it was tested in Macaques in phase I I think 10 and they had no significant changes in systemic DHT or T, so it seems like from the very little data we do have that it is potentially safe, but again, who really knows. Also, what is up with all these cucky bro type dudes promoting it on Youtube? Did you find and solution? Many world-renowned hair transplant surgeons believe topical anti-androgens will become the gold standard in the future, which leaves many questioning where RU falls in efficacy and safety. However, the odd thing is that the results of this study were never published, but a second phase trial still went through. Recommended Posts. Now, some may speculate that it's because of efficacy, while others may speculate it's because of the side effects. Topical Application: Instead of taking a pill or opting for invasive procedures, users apply RU directly to the scalp. You mean the CEO's statements? Sign up for a new account in our community. I think the CEO said after phase 2, and before the drug was abandoned, that it outperformed fin at 6 months, and I personally believe it was probably just too similar or maybe even less effective than finasteride and so it was deemed to be unprofitable, or something along those lines anyway rather than because it was unsafe. Research and Development Originally developed as a potential treatment for androgenetic alopecia, RU has undergone various studies to assess its effectiveness and safety.

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Could someone enlighten me about the company that was developping RU and suddenly decided to drop it? They speak french. To understand how RU works, let's look at the steps to hair loss:. Heart failure and lung scarring sounds like pure scaremongering from guys too afraid of using the drug. RU is classified as an anti-androgen, which means it hinders the effects of androgens, particularly dihydrotestosterone DHT. Reports of interstitial changes, including pulmonary fibrosis that led to hospitalization and death, have been reported rarely in postmarketing. I've been doing RU continuously for almost 3 years. Ideally, RU should be applied daily, and applying it at night before bedtime is suggested for convenience. Users should consult with a healthcare professional to ensure compatibility with their existing routines. RU Side Effects Unfortunately, because the clinical trials were never publicly published, we only have online are purely anecdotal. Register a new account. Oral Medication: RU offers a non-invasive option through topical application, while Finasteride requires oral ingestion, potentially leading to systemic side effects. Due to its nature as a research chemical, it might not be as widely accessible as over-the-counter products.